Open AccessComparative Morphometric Analysis of Experimental Plague Infection Caused by <i>Yersinia pestis</i> Strains with Different Genetic Characteristics
Author(s) -
С. А. Бугоркова,
V. E. Kouklev,
Т. В. Бугоркова,
Z. V. Malykhina,
Владимир Кутырев
Publication year - 2008
Publication title -
problemy osobo opasnyh infekcij
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.16
H-Index - 3
eISSN - 2658-719X
pISSN - 0370-1069
DOI - 10.21055/0370-1069-2008-4(98)-49-53
Subject(s) - yersinia pestis , plague (disease) , biology , virology , infectious process , genetics , virulence , pathology , medicine , gene
Data on adaptive-compensatory process formation in detoxication and adaptation functional systems of test animals during the plague infection modeling were obtained by means of morphometric analysis. The latter included characterization of apudocytes condition in the number of organs. Changes of apudocytes activity and quantity in immunocompetent organs and pulmonary tissue of biomodels were determined. Morphometric indices selected for registration were shown to allow characterizing the severity of experimental infectious process.