Open AccessWhat Should an Ideal Vaccine Postlicensure Safety System Be?
Author(s) -
Marie R. Griffin,
M. Miles Braun,
Kenneth J. Bart
Publication year - 2009
Publication title -
american journal of public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.284
H-Index - 264
eISSN - 1541-0048
pISSN - 0090-0036
DOI - 10.2105/ajph.2008.143081
Subject(s) - food and drug administration , vaccine safety , medicine , advisory committee , postmarketing surveillance , disease control , environmental health , public health , vaccination , family medicine , immunization , political science , adverse effect , immunology , nursing , public administration , antigen
In 2007 the National Vaccine Program, along with the Centers for Disease Control and Prevention, the Food and Drug Administration, the National Institutes of Health, and the Health Resources and Services Administration, sponsored a public conference titled "Vaccine Safety Evaluation: Post Marketing Surveillance." The objective was to discuss enhanced approaches to postlicensure evaluation of vaccine safety, including active and passive surveillance systems and special studies. The conference participants reviewed the evolution of the assessment of vaccine safety, detailed current national approaches to postmarketing safety, and offered new approaches to evaluating vaccine safety. A number of the participants recommended that information systems be expanded to include reliable information on vaccination and health outcomes in large populations. We summarize the major meeting presentations and discussions.