Open AccessPatterns and risks of postoperative recurrence in completely resected EGFR-mutant non-small cell lung cancer: prognostic significance of routine immunohistochemical markers
Author(s) -
Jianjiao Ni,
Tiantian Guo,
Yuan Li,
Xi Yang,
Yida Li,
Liang Zou,
Li Chu,
Xiao Chu,
Shuyan Li,
Luxi Ye,
Yawei Zhang,
Zhengfei Zhu
Publication year - 2019
Publication title -
translational lung cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 41
eISSN - 2226-4477
pISSN - 2218-6751
DOI - 10.21037/tlcr.2019.12.02
Subject(s) - medicine , lymphovascular invasion , oncology , proportional hazards model , lung cancer , immunohistochemistry , stage (stratigraphy) , adjuvant therapy , nomogram , radiation therapy , cancer , metastasis , paleontology , biology
Recent studies indicate that EGFR-mutant non-small cell lung cancer (NSCLC) is a heterogeneous disease with varying prognosis. In order to design an optimized surveillance strategy and identify potential candidates for adjuvant therapy, the patterns and risks of postoperative recurrence in completely resected EGFR-mutant NSCLC should be investigated, which are currently largely unknown.