Open AccessCarcinoembryonic antigen and CYFRA 21-1 responses as prognostic factors in advanced non-small cell lung cancer
Author(s) -
Akihiro Yoshimura,
Junichi Uchino,
Kôichi Hasegawa,
Taisuke Tsuji,
Shinsuke Shiotsu,
Tatsuya Yuba,
Chieko Takumi,
Tadaaki Yamada,
K. Takayama,
Noriya Hiraoka
Publication year - 2019
Publication title -
translational lung cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 41
eISSN - 2226-4477
pISSN - 2218-6751
DOI - 10.21037/tlcr.2019.06.08
Subject(s) - carcinoembryonic antigen , medicine , cytokeratin , lung cancer , univariate analysis , oncology , gastroenterology , multivariate analysis , antigen , tumor marker , cancer , immunohistochemistry , immunology
It is unclear whether changes in serum tumor marker expression post-treatment are of prognostic value. We investigated the associations between changes in serum carcinoembryonic antigen (CEA) and cytokeratin 19 fragment (CYFRA 21-1) after first-line treatment and overall survival (OS) in non-small cell lung cancer (NSCLC).