A quantitative method for assessing smoke associated molecular damage in lung cancers
Author(s) -
Kai Song,
Jia-Hao Bi,
Zhe-Wei Qiu,
Rui Felizardo,
Luc Girard,
John D. Minna,
Adi F. Gazdar
Publication year - 2018
Publication title -
translational lung cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 41
eISSN - 2226-4477
pISSN - 2218-6751
DOI - 10.21037/tlcr.2018.07.01
Subject(s) - medicine , lung cancer , kras , tobacco smoke , adenocarcinoma , oncology , lung , ercc1 , pathology , cancer , environmental health , gene , genetics , biology , colorectal cancer , dna repair , nucleotide excision repair
While tobacco exposure is the cause of the vast majority of lung cancers, an important percentage arise in lifetime never smokers. Documenting the precise extent of tobacco induced molecular changes may be of importance. Also, the contribution of environmental tobacco smoke (ETS) is difficult to assess.
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