Genome-wide copy number analyses of samples from LACE-Bio project identify novel prognostic and predictive markers in early stage non-small cell lung cancer | Zendy

Federico Rotolo | Zendy; ChangQi Zhu | Zendy; Élisabeth Brambilla | Zendy; Stephen L. Graziano | Zendy; Ken A. Olaussen | Zendy; T. Lechevalier | Zendy; JeanPierre Pig | Zendy; Robert A. Kratzke | Zendy; JeanCharles Soria | Zendy; Frances A. Shepherd | Zendy; Lesley Seymour | Zendy; Stefan Michiels | Zendy; MingSound Tsao | Zendy

Open Access

Genome-wide copy number analyses of samples from LACE-Bio project identify novel prognostic and predictive markers in early stage non-small cell lung cancer

Author(s) -

Federico Rotolo,

ChangQi Zhu,

Élisabeth Brambilla,

Stephen L. Graziano,

Ken A. Olaussen,

T. Lechevalier,

JeanPierre Pig,

Robert A. Kratzke,

JeanCharles Soria,

Frances A. Shepherd,

Lesley Seymour,

Stefan Michiels,

MingSound Tsao

Publication year - 2018

Publication title -

translational lung cancer research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.474

H-Index - 41

eISSN - 2226-4477

pISSN - 2218-6751

DOI - 10.21037/tlcr.2018.05.01

Subject(s) - molecular inversion probe , cdkn2a , medicine , adenocarcinoma , lung cancer , oncology , stage (stratigraphy) , stk11 , hazard ratio , cancer , gene , biology , single nucleotide polymorphism , genetics , kras , confidence interval , colorectal cancer , paleontology , genotype

Adjuvant chemotherapy (ACT) provides modest benefit in resected non-small cell lung cancer (NSCLC) patients. Genome-wide studies have identified gene copy number aberrations (CNA), but their prognostic implication is unknown.

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