Open AccessRapamycin downregulates NKG2D ligands in acute myeloid leukemia cells via an activation of the STAT3 pathway: a potential mechanism for rapamycin-induced immune escape in leukemia
Author(s) -
Zhichao Zhu,
Yu Bai,
Xuzhang Lu,
Jun Ding,
Chunjian Qi
Publication year - 2019
Publication title -
translational cancer research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.254
H-Index - 30
eISSN - 2219-6803
pISSN - 2218-676X
DOI - 10.21037/tcr.2019.03.01
Subject(s) - nkg2d , myeloid leukemia , pi3k/akt/mtor pathway , cancer research , k562 cells , decitabine , flow cytometry , leukemia , biology , downregulation and upregulation , cytotoxic t cell , chemistry , signal transduction , microbiology and biotechnology , immunology , gene expression , dna methylation , biochemistry , in vitro , gene