Role of androgens for urethral homeostasis | Zendy

Matthias D. Hofer | Zendy; Allen F. Morey | Zendy

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Role of androgens for urethral homeostasis

Author(s) -

Matthias D. Hofer,

Allen F. Morey

Publication year - 2018

Publication title -

translational andrology and urology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.721

H-Index - 27

eISSN - 2223-4691

pISSN - 2223-4683

DOI - 10.21037/tau.2018.02.05

Subject(s) - testosterone (patch) , medicine , cd31 , androgen receptor , urology , high power field , endocrinology , androgen , atrophy , urethral sphincter , homeostasis , angiogenesis , immunohistochemistry , urethra , hormone , prostate cancer , cancer

We observed that patients with hypogonadism are at higher risk to experience artificial urinary sphincter cuff erosion. Sphincter erosions have been found to be associated with urethral atrophy or compromised urethras subsequent to events limiting its blood supply. We therefore analyzed possible mechanisms how a decrease in testosterone serum levels can result decreased urethral blood flow.

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