Open AccessRole of androgens for urethral homeostasis
Author(s) -
Matthias Hofer,
Allen F. Morey
Publication year - 2018
Publication title -
translational andrology and urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.721
H-Index - 27
eISSN - 2223-4691
pISSN - 2223-4683
DOI - 10.21037/tau.2018.02.05
Subject(s) - testosterone (patch) , medicine , cd31 , androgen receptor , urology , high power field , endocrinology , androgen , atrophy , urethral sphincter , homeostasis , angiogenesis , immunohistochemistry , urethra , hormone , prostate cancer , cancer
We observed that patients with hypogonadism are at higher risk to experience artificial urinary sphincter cuff erosion. Sphincter erosions have been found to be associated with urethral atrophy or compromised urethras subsequent to events limiting its blood supply. We therefore analyzed possible mechanisms how a decrease in testosterone serum levels can result decreased urethral blood flow.