Open AccessImaging of glutamate in acute traumatic brain injury using chemical exchange saturation transfer
Author(s) -
Yifei Mao,
Zerui Zhuang,
Yanzi Chen,
Xiaolei Zhang,
Yuanyu Shen,
Guangyu Lin,
Renhua Wu
Publication year - 2019
Publication title -
quantitative imaging in medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 21
eISSN - 2223-4292
pISSN - 2223-4306
DOI - 10.21037/qims.2019.09.08
Subject(s) - magnetic resonance imaging , medicine , traumatic brain injury , cognition , montreal cognitive assessment , glutamate receptor , magnetization transfer , white matter , effects of sleep deprivation on cognitive performance , anesthesia , cognitive impairment , psychiatry , radiology , receptor
Chemical exchange saturation transfer (CEST) is an important contrast mechanism in the field of magnetic resonance imaging. Herein, we used CEST for glutamate (GluCEST) imaging to evaluate the Glu alterations in acute mild to moderate traumatic brain injury (TBI) and correlated such alterations with the cognitive outcome at 1-month postinjury.