Open Access3D Multi-Echo Dixon technique for simultaneous assessment of liver steatosis and iron overload in patients with chronic liver diseases: a feasibility study
Author(s) -
Fubi Hu,
Ronghua Yang,
Zixing Huang,
Min Wang,
Fang Yuan,
Chunchao Xia,
Wei Yi,
Bin Song
Publication year - 2019
Publication title -
quantitative imaging in medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 21
eISSN - 2223-4292
pISSN - 2223-4306
DOI - 10.21037/qims.2019.05.20
Subject(s) - siderosis , steatosis , medicine , fibrosis , fatty liver , steatohepatitis , gastroenterology , pathology , magnetic resonance imaging , receiver operating characteristic , radiology , disease
Patients with chronic liver diseases (CLDs) often suffer from lipidosis or siderosis. Proton density fat fraction (PDFF) and R2* can be used as quantitative parameters to assess the fat/iron content of the liver. The aim of this study was to evaluate the influence of liver fibrosis and inflammation on the 3D Multi-echo Dixon (3D ME Dixon) parameters (MRI-PDFF and R2*) in patients with CLDs and to determine the feasibility of 3D ME Dixon technique for the simultaneous assessment of liver steatosis and iron overload using histopathologic findings as the reference standard.