Open AccessHepatic iron overload identified by magnetic resonance imaging-based T2* is a predictor of non-diagnostic elastography
Author(s) -
Hassan Ghoz,
Paul T. Kröner,
Fernando Stancampiano,
Andrew W. Bowman,
Prakash Vishnu,
Michael G. Heckman,
Nancy N. Diehl,
Ethan McLeod,
Naveed Nikpour,
William C. Palmer
Publication year - 2019
Publication title -
quantitative imaging in medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 21
eISSN - 2223-4292
pISSN - 2223-4306
DOI - 10.21037/qims.2019.05.13
Subject(s) - magnetic resonance elastography , magnetic resonance imaging , elastography , medicine , radiology , nuclear magnetic resonance , pathology , ultrasound , physics
Magnetic resonance elastography (MRE) is a non-invasive test used to assess liver stiffness and fibrosis in chronic liver disease, which includes systemic iron overload. However, iron deposition by itself is associated with technical failure of MRE of the liver which necessitates the use of invasive liver biopsy as an alternative monitoring method for these patients. T2*-weighted magnetic resonance imaging (T2*) is a reliable modality to asses for hepatic as well as total body iron overload. Therefore, we aimed to determine a cutoff value on the T2* reading at which MRE would no longer provide accurate stiffness measurements in patients with iron overload.