Open AccessOptical coherence tomography correlates multiple measures of tissue damage following acute burn injury
Author(s) -
Anthony J. Deegan,
Samuel P. Mandell,
Ke Wang
Publication year - 2019
Publication title -
quantitative imaging in medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 21
eISSN - 2223-4292
pISSN - 2223-4306
DOI - 10.21037/qims.2019.04.19
Subject(s) - microangiography , optical coherence tomography , burn injury , edema , biomedical engineering , medicine , soft tissue , pathology , materials science , radiology , surgery
The visual assessment of burned skin is inherently subjective, and whilst a number of imaging modalities have identified quantifiable parameters to characterize vascular and structural changes following burn damage, none have become common place in the assessment protocol. Here, we use optical coherence tomography (OCT)-based angiography (OCTA) to introduce novel correlations between vessel depth, i.e., the depth of functional blood vessels beneath the tissue surface, edema depth, i.e., the depth of interstitial fluid buildup beneath the tissue surface, and tissue injury depth, i.e., the depth of collagen denaturation beneath the tissue surface, following burn injury.