Open AccessIntravoxel incoherent motion derived liver perfusion/diffusion readouts can be reliable biomarker for the detection of viral hepatitis B induced liver fibrosis
Author(s) -
Ting Li,
Nazmi Che-Nordin,
Yì Xiáng J. Wáng,
Pengfei Rong,
Shi-Wen Qiu,
Sheng-Wang Zhang,
Pan Zhang,
Yongfang Jiang,
Olivier Chevallier,
Feng Zhao,
Xiao-Yi Xiao,
Wei Wang
Publication year - 2019
Publication title -
quantitative imaging in medicine and surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.766
H-Index - 21
eISSN - 2223-4292
pISSN - 2223-4306
DOI - 10.21037/qims.2019.02.11
Subject(s) - intravoxel incoherent motion , medicine , hepatocellular carcinoma , fibrosis , stage (stratigraphy) , liver biopsy , biopsy , gastroenterology , perfusion , pathology , radiology , diffusion mri , magnetic resonance imaging , paleontology , biology
Recent two studies reported that intravoxel incoherent motion (IVIM) analysis can separate healthy livers and viral hepatitis B (VHB) induced liver fibrosis. However, in these two studies the starting b value for bi-exponential decay analysis was b =10 and 15 s/mm 2 respectively. The current study has two primary aims. The first is to further confirm the diagnostic value of IVIM in detecting liver fibrosis. The second is to test whether by sampling very low b value densely, then b =0 s/mm 2 image could be included to improve IVIM's diagnostic performance.