Open AccessThe Cancer Genome Atlas dataset-based analysis of aberrantly expressed genes by GeneAnalytics in thymoma associated myasthenia gravis: focusing on T cells
Author(s) -
Jianying Xi,
Liang Wang,
Chong Yan,
Jie Song,
Yang Song,
Ji Chen,
Yaping Zhu,
Zhiming Chen,
Jennifer Chun,
Jianyong Ding,
Chongbo Zhao
Publication year - 2019
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2019.06.01
Subject(s) - thymoma , myasthenia gravis , gene , phenotype , btla , reverse transcription polymerase chain reaction , medicine , pathogenesis , biology , cancer research , gene expression , immunology , genetics , t cell , immune system
Myasthenia gravis (MG) is a group of autoimmune disease which could be accompanied by thymoma. Many differences have been observed between thymoma-associated MG (TAMG) and non-MG thymoma (NMG). However, the molecular difference between them remained unknown. This study aimed to explore the differentially expressed genes (DEGs) between the two categories and to elucidate the possible pathogenesis of TAMG further.