Open AccessControlled automated reperfusion of the whole body after cardiac arrest
Author(s) -
Christian Trummer,
Christoph Benk,
Friedhelm Beyersdorf
Publication year - 2019
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2019.04.05
Subject(s) - medicine , extracorporeal cardiopulmonary resuscitation , resuscitation , cardiopulmonary resuscitation , extracorporeal circulation , reperfusion injury , extracorporeal , ischemia , cardiology , surgery
Sudden circulatory arrest (CA) requiring cardiopulmonary resuscitation (CPR) has for decades been associated with high mortality and frequent neurological sequelae in the rarer survivors. The high mortality and morbidity are potentially related to a severe and global ischemia/reperfusion injury (IRI) of the whole body, especially the brain. Consequently, strategies to counteract this severe IRI may improve survival and neurological recovery of affected patients.