Additional role of bronchial mucosal biopsy for ciliary structural abnormality in diagnosis of primary ciliary dyskinesia | Zendy

HyunIl Gil | Zendy; Taebum Lee | Zendy; ByeongHo Jeong | Zendy; Hyun Lee | Zendy; Junsu Choe | Zendy; Kangmo Ahn | Zendy; Sang Duk Hong | Zendy; Kyeongman Jeon | Zendy; WonJung Koh | Zendy; JungSun Kim | Zendy; Hye Yun Park | Zendy

Open Access

Additional role of bronchial mucosal biopsy for ciliary structural abnormality in diagnosis of primary ciliary dyskinesia

Author(s) -

HyunIl Gil,

Taebum Lee,

ByeongHo Jeong,

Hyun Lee,

Junsu Choe,

Kangmo Ahn,

Sang Duk Hong,

Kyeongman Jeon,

WonJung Koh,

JungSun Kim,

Hye Yun Park

Publication year - 2019

Publication title -

journal of thoracic disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 60

eISSN - 2077-6624

pISSN - 2072-1439

DOI - 10.21037/jtd.2019.02.24

Subject(s) - medicine , biopsy , mucous membrane of nose , primary ciliary dyskinesia , nose , nasal cavity , pathology , sinusitis , bronchiectasis , surgery , lung

Transmission electron microscopy (TEM) is one of diagnostic tests for primary ciliary dyskinesia (PCD). The mucosal samples obtained for cilia examination are generally procured from the nasal turbinate, but these specimens often yield inadequate results. The bronchial mucosa is recognized as an alternative sample, but no study has examined the additional utility of bronchial mucosa compared with nasal mucosa in the diagnosis of PCD.

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