Open AccessAdditional role of bronchial mucosal biopsy for ciliary structural abnormality in diagnosis of primary ciliary dyskinesia
Author(s) -
Hyun Il Gil,
Taebum Lee,
Byeong Ho Jeong,
Hyun Lee,
Junsu Choe,
Kangmo Ahn,
Sang Duk Hong,
Kyeongman Jeon,
Won Jung Koh,
Jung Sun Kim,
Hye Yun Park
Publication year - 2019
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2019.02.24
Subject(s) - medicine , biopsy , mucous membrane of nose , primary ciliary dyskinesia , nose , nasal cavity , pathology , sinusitis , bronchiectasis , surgery , lung
Transmission electron microscopy (TEM) is one of diagnostic tests for primary ciliary dyskinesia (PCD). The mucosal samples obtained for cilia examination are generally procured from the nasal turbinate, but these specimens often yield inadequate results. The bronchial mucosa is recognized as an alternative sample, but no study has examined the additional utility of bronchial mucosa compared with nasal mucosa in the diagnosis of PCD.