Open AccessA novel prognostic marker in patients with non-small cell lung cancer: musculo-immuno-nutritional score calculated by controlling nutritional status and creatine kinase
Author(s) -
Shinkichi Takamori,
Gouji Toyokawa,
Mototsugu Shimokawa,
Fumihiko Kinoshita,
Yuka Kozuma,
Taichi Matsubara,
Naoki Haratake,
Takaki Akamine,
Fumihiko Hirai,
Tetsuzo Tagawa,
Yoshinao Oda,
Yoshihiko Maehara
Publication year - 2019
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2019.01.76
Subject(s) - medicine , lung cancer , gastroenterology , sma* , biomarker , oncology , mathematics , combinatorics , biochemistry , chemistry
Controlling nutritional status (CONUT) and skeletal muscle area (SMA) are both useful prognostic factors in patients with non-small cell lung cancer (NSCLC). We hypothesized that low serum creatine kinase (CK) would be a surrogate of decreased SMA, and defined a novel prognostic factor, CONUT/CK score (CNKS). The aim of this study was to elucidate the clinical significance of CNKS in NSCLC patients.