Open AccessProphylactic cranial irradiation is associated with improved survival following resection for limited stage small cell lung cancer
Author(s) -
Benjamin J. Resio,
Jessica R. Hoag,
Alexander S. Chiu,
Andres F. Monsalve,
Andrew P. Dhanasopon,
Daniel J. Boffa,
Justin D. Blasberg
Publication year - 2019
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2019.01.64
Subject(s) - medicine , conventional pci , prophylactic cranial irradiation , proportional hazards model , hazard ratio , surgery , survival analysis , chemotherapy , stage (stratigraphy) , lymph node , cancer , lung cancer , oncology , confidence interval , myocardial infarction , paleontology , biology
Brain metastases are a major cause of mortality in patients with small cell lung cancer (SCLC). Prophylactic cranial irradiation (PCI) may improve survival among patients that respond to chemotherapy. Less is known about the outcomes of PCI following surgical resection of SCLC. The purpose of this study was to determine if patients who underwent initial surgical resection of SCLC benefit from PCI.