Open AccessMicroRNA-374b inhibits the tumor growth and promotes apoptosis in non-small cell lung cancer tissue through the p38/ERK signaling pathway by targeting JAM-2
Author(s) -
Yujun Wang,
Lijuan Yu,
Tao Wang
Publication year - 2018
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2018.09.93
Subject(s) - microrna , viability assay , cancer research , apoptosis , carcinogenesis , tunel assay , cell growth , mapk/erk pathway , biology , lung cancer , cancer , medicine , signal transduction , microbiology and biotechnology , pathology , biochemistry , gene
MicroRNAs (miRNAs) are reportedly involved in various cancers. The present study aimed to investigate the role of miRNA-374b in cell viability, proliferation, apoptosis, and tumor formation in non-small cell lung cancer (NSCLC) in humans.