Open AccessClinical predictors of the effectiveness of tiotropium in adults with symptomatic asthma: a real-life study
Author(s) -
Wen Cheng,
Bing Wu,
Wei Liao,
Chih-Yu Chen,
Wei Chun Chen,
TeChun Hsia,
ChihYen Tu,
Chia-Hung Chen,
Wu Huei Hsu
Publication year - 2018
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2018.05.139
Subject(s) - medicine , tiotropium bromide , asthma , copd , exacerbation , logistic regression , lama , eosinophil , univariate analysis , multivariate analysis , lung function , lung
Long-acting muscarinic antagonist (LAMA) tiotropium improved lung function and reduced risks of exacerbation when added on to inhaled corticosteroids (ICS) with or without long-acting B 2 agonists (LABAs) in patients with uncontrolled asthma. However, studies predicting the effectiveness of tiotropium based on patients' clinical characteristics were limited.