Open AccessPrognostic implication of FEV1/FVC ratio for limited-stage small cell lung cancer
Author(s) -
Oyeon Cho,
YoungTaek Oh,
Mison Chun,
O Kyu Noh,
Jaesung Heo
Publication year - 2018
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2018.02.14
Subject(s) - medicine , hazard ratio , vital capacity , lung cancer , confidence interval , copd , stage (stratigraphy) , oncology , chemoradiotherapy , gastroenterology , cancer , lung , lung function , paleontology , diffusing capacity , biology
A proportion of patients with chronic obstructive pulmonary disease (COPD) may progress rapidly to small cell lung cancer (SCLC). As the forced expiratory volume in 1 second (FEV1)/forced volume vital capacity (FVC) ratio is usually impaired in patients with COPD, and given that the FEV1 and FVC are not necessarily related to lung cancer development, we performed this study to test our hypothesis that the FEV1/FVC ratio predicts survival of patients with limited-stage (LS)-SCLC.