Open AccessArgatroban administration as therapy for thrombosis in patients with continuous-flow ventricular assist devices
Author(s) -
Leonhard Wert,
Jasmin S. Hanke,
Güneş Doğan,
Marcel Ricklefs,
Arijit Chatterjee,
C. Feldmann,
Ismail A. Ismail,
L. Christian Napp,
Axel Haverich,
Jan D. Schmitto
Publication year - 2018
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2017.10.164
Subject(s) - argatroban , medicine , thrombosis , thrombus , ventricular assist device , surgery , cardiology , heart failure , thrombin , platelet
Device thrombosis is one of the main complications in left ventricular assist devices (LVAD) therapy and remains a challenging issue. Data on device thrombosis management, especially on the application of direct thrombin inhibitors such as argatroban, is limited and a consensus on thrombosis management has not yet been established.