Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-κB signaling pathway | Zendy

Jian Wang | Zendy; Jian-an Huang | Zendy; Linlin Wang | Zendy; Cuicui Chen | Zendy; Dong Yang | Zendy; Meiling Jin | Zendy; Chunxue Bai | Zendy; Yuanlin Song | Zendy

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Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-κB signaling pathway

Author(s) -

Jian Wang,

Jian-an Huang,

Linlin Wang,

Cuicui Chen,

Dong Yang,

Meiling Jin,

Chunxue Bai,

Yuanlin Song

Publication year - 2017

Publication title -

journal of thoracic disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 60

eISSN - 2077-6624

pISSN - 2072-1439

DOI - 10.21037/jtd.2017.09.135

Subject(s) - mapk/erk pathway , proinflammatory cytokine , inflammation , bronchoalveolar lavage , p38 mitogen activated protein kinases , nf κb , reactive oxygen species , signal transduction , medicine , oxidative stress , immunology , pharmacology , chemistry , microbiology and biotechnology , lung , biology

Particulate matter (PM) is a high risk factor for various respiratory diseases and triggers an inflammatory response in lung tissues. However, the molecular mechanism of the PM-induced inflammatory response is incompletely understood.

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