Open AccessProton beam therapy versus stereotactic body radiotherapy for hepatocellular carcinoma: practice patterns, outcomes, and the effect of biologically effective dose escalation
Author(s) -
Shaakir Hasan,
Stephen Abel,
Vivek Verma,
Patrick Webster,
W. Tristram Arscott,
Rodney E. Wegner,
Alexander Kirichenko,
Charles B. Simone
Publication year - 2019
Publication title -
journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.084
H-Index - 39
eISSN - 2219-679X
pISSN - 2078-6891
DOI - 10.21037/jgo.2019.08.03
Subject(s) - medicine , hepatocellular carcinoma , proportional hazards model , prospective cohort study , radiation therapy , hazard ratio , surgery , oncology , confidence interval
Stereotactic body radiation therapy (SBRT) and proton beam therapy (PBT) generally are safe and effective for non-operative hepatocellular carcinoma (HCC). To date, data comparing the two modalities are limited. We aimed to identify the practice patterns and outcomes of nonsurgical HCC cases treated definitively with either SBRT or PBT.