Open AccessLocal excision for patients with stage I anal canal squamous cell carcinoma can be curative
Author(s) -
Sakti Chakrabarti,
Zhaohui Jin,
Brandon M. Huffman,
Siddhartha Yadav,
Rondell P. Graham,
Dora Lam-Himlin,
Amy L. Lightner,
Christopher L. Hallemeier,
Amit Mahipal
Publication year - 2019
Publication title -
journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.084
H-Index - 39
eISSN - 2219-679X
pISSN - 2078-6891
DOI - 10.21037/jgo.2018.12.12
Subject(s) - medicine , anal canal , cohort , stage (stratigraphy) , surgery , wide local excision , retrospective cohort study , rectum , paleontology , biology
Definitive concurrent chemoradiation is the current standard of care for all stage I anal canal squamous cell carcinoma. Local excision as primary treatment for selected stage I lesions has been reported in the literature but is not currently recommended by major guidelines. We herein compared the oncologic outcomes of patients with stage I anal canal squamous cell carcinoma treated with local excision alone versus chemoradiation to determine if there are any significant differences in outcomes including disease free survival, overall survival (OS) and local failure rate.