Comprehensive molecular profiling of extrahepatic cholangiocarcinoma in Chinese population and potential targets for clinical practice | Zendy

Xue Liang | Zendy; Chao Guo | Zendy; Kang Zhang | Zendy; Hang Jiang | Zendy; Fei Pang | Zendy; Ying Dou | Zendy; Xiaoyan Liu | Zendy; Hanqing Lin | Zendy; Xiaowei Dong | Zendy; Songhui Zhao | Zendy; Ming Yao | Zendy; Kai Wang | Zendy; Yujie Feng | Zendy; Weiguang Gu | Zendy

Open Access

Comprehensive molecular profiling of extrahepatic cholangiocarcinoma in Chinese population and potential targets for clinical practice

Author(s) -

Xue Liang,

Chao Guo,

Kang Zhang,

Hang Jiang,

Fei Pang,

Ying Dou,

Xiaoyan Liu,

Hanqing Lin,

Xiaowei Dong,

Songhui Zhao,

Ming Yao,

Kai Wang,

Yujie Feng,

Weiguang Gu

Publication year - 2019

Publication title -

hepatobiliary surgery and nutrition

Language(s) - English

Resource type - Journals

eISSN - 2304-389X

pISSN - 2304-3881

DOI - 10.21037/hbsn.2019.08.05

Subject(s) - cdkn2a , kras , medicine , arid1a , cohort , oncology , population , targeted therapy , cancer research , mapk/erk pathway , chinese population , bioinformatics , gene , mutation , genotype , cancer , genetics , biology , kinase , colorectal cancer , environmental health

Cholangiocarcinoma (CCA) is a diverse group of malignancies arising from the intra- or extrahepatic biliary epithelium and characterized by its late diagnosis and fatal outcome. Extrahepatic cholangiocarcinoma (ECC) accounts for 90% of CCA. However, little is known about the comprehensive genomic alterations of ECC in Chinese population for providing clinical managements especially targeted therapy.

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