Open AccessThe use of tranexamic acid in microsurgery—is it safe?
Author(s) -
Alessia M. Lardi,
Kathrin Dreier,
Klaus Junge,
Jian Farhadi
Publication year - 2018
Publication title -
gland surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.643
H-Index - 22
eISSN - 2227-8575
pISSN - 2227-684X
DOI - 10.21037/gs.2018.03.10
Subject(s) - medicine , tranexamic acid , microsurgery , surgery , antifibrinolytic , anesthesia , thrombosis , perioperative , blood loss
An appropriate and adequate blood flow and oxygen delivery is paramount to free flap viability and success. The perioperative use of tranexamic acid (TXA) is associated with less risk for blood loss and blood transfusion in trauma, gynaecology, ear nose and throat (ENT) and orthopaedic surgery. As an antifibrinolytic drug, TXA has generally been avoided in microsurgery. The aim of this study is to evaluate the safety and benefit of using TXA in microsurgery.