Open AccessAntibody to oxidized low-density lipoprotein inhibits THP1 cells from apoptosis by suppressing NF-κB pathway activation
Author(s) -
Rui Dai,
Jing Dong,
Weijuan Li,
Yanxiang Zhou,
Wei Zhou,
Wenping Zhou,
Manhua Chen
Publication year - 2019
Publication title -
cardiovascular diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.83
H-Index - 22
eISSN - 2223-3660
pISSN - 2223-3652
DOI - 10.21037/cdt.2019.08.01
Subject(s) - apoptosis , antibody , flow cytometry , microbiology and biotechnology , lipoprotein , inflammation , medicine , blot , phorbol , low density lipoprotein , endocrinology , immunology , chemistry , signal transduction , protein kinase c , biology , biochemistry , cholesterol , gene
This study aimed to investigate whether the oxidized low-density lipoprotein (Ox-LDL) antibody is able to inhibit THP1 cell apoptosis by suppressing NF-κB pathway.