Open AccessDoppler echocardiographic assessment of pulmonary artery pressure in children with sickle cell anaemia
Author(s) -
Moriam Omolola Lamina,
Barakat Adeola Animasahun,
Ijeoma Nnena Akinwumi,
OF Njokanma
Publication year - 2019
Publication title -
cardiovascular diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.83
H-Index - 22
eISSN - 2223-3660
pISSN - 2223-3652
DOI - 10.21037/cdt.2019.04.02
Subject(s) - medicine , pulmonary artery , doppler echocardiography , pulmonary hypertension , pediatrics , cardiology , sickle cell anemia , blood pressure , disease , diastole
Pulmonary artery hypertension (PAH) is a known complication of patients with sickle cell disease (SCD). The prevalence of PAH has been reported to be high in children with SCD in developed countries. The mortality rate of patients with SCD who develop PAH is said to be 40% at 24 to 40 months after diagnosis. In Sub-Saharan Africa, particularly Nigeria, where the prevalence of SCD is high, there is a dearth of data on the prevalence of PAH in children with SCD. PAH may be a likely contributor to the unacceptably high mortality rate of children with SCD in Africa. The present study aimed to determine the pattern of pulmonary artery pressure in children with sickle cell anaemia (SCA) aged 1 to 12 years in their steady state using Doppler echocardiography in our environment.