Open AccessAir pollution and telomere length: a systematic review of 12,058 subjects
Author(s) -
Bing Zhao,
Ha Q. Vo,
Fay H. Johnston,
Kazuaki Negishi
Publication year - 2018
Publication title -
cardiovascular diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.83
H-Index - 22
eISSN - 2223-3660
pISSN - 2223-3652
DOI - 10.21037/cdt.2018.06.05
Subject(s) - medicine , telomere , air pollution , buccal swab , pollution , cohort study , tobacco smoke , environmental health , physiology , genetics , biology , dna , ecology
Over recent decades, adverse effects of ambient air pollution on the cardiovascular system have been clearly demonstrated. However, the underlying mechanisms are not fully elucidated. Air pollution may accelerates biological aging and thereby the susceptibility to cardiovascular diseases (CVDs). Telomeres are tandem repetitive DNA complexes that play a critical role in maintaining chromosome stability. There are, however, heterogeneities among the reported effects of air pollution on telomere. This study sought to evaluate the existing literature on the association between air pollution and telomere length (TL).