Open AccessLiver enzyme trends in patients taking uninterrupted metformin before and after coronary surgery
Author(s) -
Rakan I. Nazer,
Mohammed Abalhassan,
Khalid A. Alburikan
Publication year - 2018
Publication title -
cardiovascular diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.83
H-Index - 22
eISSN - 2223-3660
pISSN - 2223-3652
DOI - 10.21037/cdt.2018.05.04
Subject(s) - medicine , metformin , biguanide , interquartile range , diabetes mellitus , alanine transaminase , aspartate transaminase , creatinine , surgery , alanine aminotransferase , gastroenterology , endocrinology , enzyme , alkaline phosphatase , biochemistry , chemistry
Metformin is an oral antidiabetic agent belonging to the biguanide class of antidiabetics. Possible novel applications for metformin in cardiovascular disease might exist. The aim of this study was to verify a possible association between pre-operative metformin administration and protection against ischemia-induced liver injury in diabetic patients undergoing coronary artery bypass grafting (CABG) surgery.