Open AccessNeutrophil-to-lymphocyte and platelet-to-lymphocyte ratios inversely correlate to clinical and pathologic stage in patients with resectable pancreatic ductal adenocarcinoma
Author(s) -
Alejandro Recio-Boiles,
Aparllagangula,
Summana Veeravelli,
Jessica Vondrak,
Kathylynn Saboda,
Denise J. Roe,
Emad Elquza,
Ali McBride,
Hani M. Babiker
Publication year - 2019
Publication title -
annals of pancreatic cancer
Language(s) - English
Resource type - Journals
ISSN - 2616-2741
DOI - 10.21037/apc.2019.06.01
Subject(s) - stage (stratigraphy) , pancreatic ductal adenocarcinoma , lymphocyte , medicine , platelet , pathology , adenocarcinoma , immunology , pancreatic cancer , biology , cancer , paleontology
Post-surgical pathology (SP) staging correlates with long-term survival. Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) have been shown to predict prognosis and extent of tumor in patients with metastatic pancreatic ductal adenocarcinoma (PDAC). This study aimed to correlate NLR and PLR to radiological clinical staging (CS), carbohydrate antigen (CA) 19-9 tumor marker and SP staging in patients with resectable-PDAC (R-PDAC); and to investigate NLR and PLR as potential markers to guide neoadjuvant therapy.