Open AccessDETERMINASI PEMBERIAN SUKROSA TERHADAP KADAR SGPT DAN SGOT TIKUS GALUR WISTAR SEBAGAI INDIKATOR FUNGSI HATI
Author(s) -
Prawita Lintang Andayani,
Koekoeh Santoso,
Nastiti Kusumorini,
Aryani Sismin Satyaningtijas,
Atin Supiyani
Publication year - 2017
Publication title -
bioma
Language(s) - English
Resource type - Journals
eISSN - 2580-9032
pISSN - 0126-3552
DOI - 10.21009/bioma12(1).8
Subject(s) - sucrose , traditional medicine , medicine , liver function , pharmacology , biology , biochemistry
The aim of the study was to determine the correlation between sucrose intake at various administration doses to SGPT and SGOT level in Wistar rats. SGPT and SGOT level in blood serum were used as parameter of liver function. Twelve rats were grouped according to administration doses (20%, 40%, 60% of given feed total energy and control group). Sucrose was administered orally once a day for 70 days at given doses by force feeding. SGPT dan SGOT level were measured using SGPT and SGOT Test Kit and read using spectrophotometer. The result indicated that increased administration dose caused a significant increase of SGPT and SGOT level.