Open AccessNEW COVID-19 CORONAVIRUS INFECTION IN A PATIENT WITH AUTOIMMUNE POLYGLANDULAR SYNDROME (clinical case)
Author(s) -
A. L. Ivanova,
И. В. Король,
Juliya S. Kovalenko,
Lidiya V. Ruzhitskaya,
M. V. Skibitskaya,
Veronica O. Petrovykh,
Ivan Yu. Tanin
Publication year - 2021
Publication title -
vestnik sovremennoj kliničeskoj mediciny
Language(s) - English
Resource type - Journals
eISSN - 2079-553X
pISSN - 2071-0240
DOI - 10.20969/vskm.2021.14(4).85-91
Subject(s) - medicine , asymptomatic , coronavirus , disease , diabetes mellitus , hydroxychloroquine , pneumonia , covid-19 , immunology , endocrinology , infectious disease (medical specialty)
Background.More than half of those infected with the new coronavirus infection COVID19 carry the disease in a mild or asymptomatic form. Patients over 60 years of age and those with comorbid chronic diseases, such as respiratory, cardiovascular, diabetes, oncological and autoimmune diseases, are susceptible to more severe forms of the disease. Aim.The aim of the study was to demonstrate the stages of clinical picture development, methods of diagnosis and treatment of the new coronavirus infection COVID19. Material and methods. We present a clinical case of a new coronavirus infection COVID19 in a 73yearold patient with autoimmune polyglandular syndrome. Results and its discussion. Aggravating background represented by arrhythmic syndrome and autoimmune polyglandular syndrome contributed to the development of a severe form of new coronavirus infection COVID19 in the patient. Complex multivector therapy aimed at pathogenetic and symptomatic treatment, according to the guidelines, in combination with magnesium and potassium medications, as well as immunemodulating therapy contributed to the patient’s recovery and rehabilitation. Conclusion. Treatment with glucocorticoids for new COVID19 coronavirus infection significantly improves the outcome of the disease. At the same time, glucocorticoid therapy can lead to progression of arrhythmic syndrome, development of druginduced hypercorticoidism, and «withdrawal» syndrome. Prevention and treatment of heart rhythm disturbances is the application of potassium and magnesium medications in sufficient doses. Gradual withdrawal of glucocorticoids over a long time under the supervision of an endocrinologist will help to restore the hypothalamicpituitaryadrenal axis.