Open AccessAntioxidants Effectivity In Skin Lotion Formulation Of Mesocarp Fruit Extract Lontar (Borassus Flabellifer) Against White Rats Wistar Male In-Situ
Author(s) -
Luthfiasari Amatullah,
Tri Nur Cahyaningrum,
Anisa Nur Fidyaningsih
Publication year - 2017
Publication title -
journal of pharmaceutical science and clinical research
Language(s) - English
Resource type - Journals
ISSN - 2503-331X
DOI - 10.20961/jpscr.v2i01.5236
Subject(s) - lotion , palm , antioxidant , positive control , chemistry , traditional medicine , food science , erythema , horticulture , biology , medicine , dermatology , biochemistry , physics , quantum mechanics
Study of bioactive mesocarp on palm fruits has been conducted previously. Therefore, this research aims to make a preparation of antioxidant skin lotion palm fruit mesocarp ( Borrasus flabellifer ) and to evaluate the effects of antioxidants on skin preparation lotion palm fruit ( Borrasus flabellifer ) by In-situ. This study was an experimental study by making a preparation of skin lotion on the stability of the corresponding and testing the antioxidant treatment with a sample of 30 rats male wistar strain. The antioxidant test was divided into 5 groups randomly: negative control (-), positive control (compound sunscreen brands parasol SPF 33), group 1 (lotio extract palm fruit mesocarp with a concentration of 0.2%), group 2 (lotio palm fruit mesocarp extract with concentration of 0.4%) and group 3 (lotio palm fruit mesocarp extract with concentration 0.8%). The results of in-situ states showed 0.8% extract of palm fruit mesocarp exhibited the least erythema score which was an average of 1.7. It was comparable to positive control which exhibited similar erythema score.