Open AccessFormulation and Evaluation of Pediatric Paracetamol Elixir Using Natural Colorant
Author(s) -
Mamatha Tirunagari,
Nagadivya Nerella,
Anupama Koneru,
Madihah,
Syed Sarfaraz,
Maryam Mushtaq
Publication year - 2020
Publication title -
international journal of pharmtech research
Language(s) - English
Resource type - Journals
eISSN - 2455-9563
pISSN - 0974-4304
DOI - 10.20902/ijptr.2019.130307
Subject(s) - elixir (programming language) , dosage form , bioavailability , traditional medicine , chemistry , chromatography , medicine , pharmacology , computer science , programming language
Oral dosage forms are most popular among other dosage forms. In terms ofbioavailability liquid dosage form is better than that of solid dosage form. In the presentscenario monophagic liquid dosage forms such as syrups, elixirs, throat paints, mouth washes,gargles have gained huge popularity. These are very basic preparations which involve briefprocesses, machineries and are cost effective also. They come in wide range colours andflavors so as to attract the pediatric age group. Currently colors derived from natural sourcesare given priority compared to synthetic ones. In this study we formulated paracetamol whichis a bitter drug as an elixir using natural colorant from annatto seeds at three differentconcentrations in F1, F2, and F3. Ethanol. Propylene glycol, mixed fruit juice, chloroformspirit, sucrose syrup and glycerin were also used. These formulations were evaluated fordifferent physical parameters and it showed good results.