Open AccessDevelopment of New Analytical Method for Estimation of Lansoprazole in Bulk and Tablet dosage forms
Author(s) -
Santosh Karajgi,
D.T. Mallikarjun,
M Somashekhar,
B. Shivakumar
Publication year - 2019
Publication title -
international journal of pharmtech research
Language(s) - English
Resource type - Journals
eISSN - 2455-9563
pISSN - 0974-4304
DOI - 10.20902/ijptr.2019.120409
Subject(s) - lansoprazole , dosage form , absorbance , chemistry , derivative (finance) , chromatography , solvent , second derivative , mathematics , pharmacology , medicine , organic chemistry , mathematical analysis , financial economics , economics , omeprazole
The present paper reports a simple, accurate and precise spectroscopic technique forestimation of Lansoprazole by first order derivative technique in tablet dosage form. Thespectroscopic method for estimation of Lansoprazole by first order derivative technique wascarried out using methyl alcohol as solvent. The absorbance maximum was 275nm. Beers lawobserved in the range of 30 - 150μg/ml concentration. The recovery studies demonstrated theaccuracy of the proposed procedure and the results were established as per ICH guidelines. Thetechnique was used successfully for the estimation of Lansoprazole in bulk and tablet and puredosage form.