Open AccessSynthesis, Characterization and Antimicrobial studies of Schiff base Ligand from amino acid L-arginine and its Cu(II), Ni(II),Co(II) complexesIJCTR.2019.130201
Author(s) -
Rekha Devi,
S. SudhaKumari
Publication year - 2020
Publication title -
international journal of chemtech research
Language(s) - English
Resource type - Journals
eISSN - 2455-9555
pISSN - 0974-4290
DOI - 10.20902/ijctr.2019.130201
Subject(s) - ligand (biochemistry) , chemistry , molar conductivity , schiff base , metal , carboxylate , octahedron , magnetic susceptibility , inorganic chemistry , nuclear chemistry , crystallography , stereochemistry , crystal structure , organic chemistry , biochemistry , receptor
Transition metal complexes of Cu(II), Ni(II), Co(II) with a Schiff base Ligand(R,Z)-2-(2-hydroxy-3-methoxybenzylideneamino)-5-guanidinopentanoic acid (HMA-GPA)was synthesized by the condensation of 2-hydroxy-3-methoxybenzaldehyde and L- Arginine.These were characterized by elemental analysis IR, UV, magnetic susceptibility and molarconductivity measurements. The IR spectra of the Ligand HMA-GPA and the metalcomplexes suggest that the Ligand coordinates the metal ion through azomethine nitrogen,carboxylate Oxygen and Oxygen of the phenolic -OH group. The electronic absorptionspectra and magnetic data indicate the Cu(II), Ni(II)complexes to be square planar and Co(II)complex to be octahedral. The metal complexes and the ligand were subjected toantimicrobial studies by Kirby Bayer Disc-diffusion method and found to have significantactivity against the selected bacterial and fungal strains under study.