Open AccessMeta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models
Author(s) -
Austin C. Conklin,
Hitoo Nishi,
Florencia Schlamp,
Tiit Örd,
Kadri Õunap,
Minna U. Kaikkonen,
Edward A. Fisher,
Casey E. Romanoski
Publication year - 2021
Publication title -
immunometabolism
Language(s) - English
Resource type - Journals
ISSN - 2633-0407
DOI - 10.20900/immunometab20210022
Subject(s) - in vivo , in vitro , transcriptome , vascular smooth muscle , microbiology and biotechnology , biology , cell , phenotype , macrophage , foam cell , cell type , genetics , gene expression , gene , smooth muscle , endocrinology
Vascular smooth muscle cells (VSMC) exhibit phenotypic plasticity in atherosclerotic plaques, and among other approaches, has been modeled in vitro by cholesterol loading.