Open AccessEpstein-Barr virus DNA loads in the peripheral blood cells predict the survival of locoregionally-advanced nasopharyngeal carcinoma patients
Author(s) -
Yanhu He,
Dawei Yang,
Ting Zhou,
WenQiong Xue,
Jiang-Bo Zhang,
Fangfang Li,
Fang Wang,
Tongmin Wang,
Ziyi Wu,
Ying Liao,
Zheng Miao,
ChangMi Deng,
DanHua Li,
Yijing Jia,
LeiLei Yuan,
Wenli Zhang,
WeiHua Jia
Publication year - 2021
Publication title -
cancer biology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.517
H-Index - 42
ISSN - 2095-3941
DOI - 10.20892/j.issn.2095-3941.2020.0464
Subject(s) - nasopharyngeal carcinoma , concordance , biomarker , oncology , proportional hazards model , medicine , viral load , population , cohort , immunology , nomogram , virus , biology , radiation therapy , biochemistry , environmental health
Circulating cell-free Epstein-Barr virus (EBV) DNA has been shown to be a valuable biomarker for population screening and prognostic surveillance for nasopharyngeal carcinoma (NPC). Despite important insights into the biology of persistence, few studies have addressed the clinical significance of cell-based EBV-DNA loads in peripheral blood cells (PBCs).