Open AccesssLe<sup>x</sup> expression in invasive micropapillary breast carcinoma is associated with poor prognosis and can be combined with MUC1/EMA as a supplementary diagnostic indicator
Author(s) -
Yawen Song,
Hui Sun,
Wu K,
Jianke Lyu,
Jingyue Zhang,
Feng Gu,
Yihui Ma,
Biyu Shen,
Chijuan Wang,
Xiaojiao Chen,
Jing Xu,
Weidong Li,
Fangfang Liu,
Fu Li
Publication year - 2021
Publication title -
cancer biology and medicine
Language(s) - English
Resource type - Journals
ISSN - 2095-3941
DOI - 10.20892/j.issn.2095-3941.2020.0422
Subject(s) - muc1 , immunohistochemistry , immunofluorescence , pathology , medicine , stage (stratigraphy) , mucin , metastasis , sialyl lewis x , oncology , biology , cancer , antibody , inflammation , immunology , paleontology , selectin
Mucin 1 (MUC1/EMA) and sialyl Lewis X (sLe x ) indicate polarity reversal in invasive micropapillary carcinoma (IMPC). The purpose of this study was to evaluate the expression of MUC1/EMA and sLe x and to assess their diagnostic and prognostic value in patients with IMPC.