Open AccessCerebrovascular mediated subclinical brain injury – interaction between cardiovascular function, brain structure and cognitive function – study rationale, design and principal methods
Author(s) -
Katarzyna Katulska,
Andrzej Mińczykowski,
Jarosław Piskorski,
Andrzej Wykrętowicz,
Marek Stajgis,
Przemysław Guzik,
Andrzej Wykrętowicz
Publication year - 2014
Publication title -
journal of medical science
Language(s) - English
Resource type - Journals
eISSN - 2353-9801
pISSN - 2353-9798
DOI - 10.20883/medical.e65
Subject(s) - subclinical infection , cognition , neuroimaging , stroke (engine) , brain structure and function , medicine , disease , traumatic brain injury , physical medicine and rehabilitation , psychology , neuroscience , cardiology , psychiatry , mechanical engineering , engineering
Project entitled “Cerebrovascular mediated subclinical brain injury – interaction between cardiovascular function, brain structure and cognitive function- study rationale, design and principal methods” is a cross-sectional study in a group of older individuals with no apparent symptoms of stroke, transient ischemic attacks or cognitive impairment. The primary aim of the projects is further our understanding of the patomechanism of cerebrovascular disease associate brain injury as well as vascular cognitive impairment and give a better insight into the interplay between arterial wall, ventriculo-vascular coupling, wave reflection and pulsatility of the flow and how these interplays are mirrored by MRI neuroimaging. With our novel, interdisciplinary approach, we will define the methodology and build tools for those who want to follow in this challenging and non-standard direction.