Open AccessImmediate and Long-term Results of Stenting of the Unprotected Left Coronary Artery Trunk in Patients with Stable Coronary Heart Disease
Author(s) -
G. К. Arutyunyan,
С И Проваторов,
Н. С. Жукова,
А. С. Терещенко,
Д. В. Огнерубов,
I. Emelyanov,
I. V. Krasnoshchekov,
А. Н. Самко
Publication year - 2019
Publication title -
vestnik rentgenologii i radiologii
Language(s) - English
Resource type - Journals
eISSN - 2619-0478
pISSN - 0042-4676
DOI - 10.20862/0042-4676-2019-100-2-82-88
Subject(s) - medicine , trunk , incidence (geometry) , adverse effect , stent , coronary artery disease , cardiology , coronary stenting , first generation , third generation , artery , surgery , percutaneous coronary intervention , restenosis , population , myocardial infarction , environmental health , ecology , telecommunications , physics , computer science , optics , biology
Objective. To assess the immediate and long-term results of stenting of the unprotected left coronary artery (LCA) trunk in patients, by using different types of drug-eluting stents. Material and methods. The follow-up covered 282 patients who had undergone stenting of the unprotected LCA trunk. The mean follow-up was 34.6 [33.9; 35.3] months. The patients were divided into groups according to the type of a first-, second-, and third-generation implanted stent. Results. The incidence of adverse cardiovascular events in the patients of Group 1 was significantly higher than in those in Groups 2 and 3 (29 and 7.6%, p <0.0001). The incidence of thrombosis of first-generation stents (7.0%) was significantly higher than that of second- and third-generation ones (1.6%) ( p =0.02). The incidence of adverse cardiovascular events was comparable between Groups 2 and 3, despite a shorter duration of dual antiplatelet therapy in the third-generation stent group. The absence of stent postdilatation in the LCA trunk is an independent risk factor for adverse prognosis. Conclusion. The use of second- and third-generation stents along with changes in the technical aspects of stenting of the unprotected LCA trunk leads to a substantial reduction in the risk of adverse cardiovascular events and allows the indications for intervention to be expanded in this patient category.