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Histochemical research of cells functionally leading tissue liver and kidneys of rats after intravenous application of nanoparticles magnetite
Author(s) -
I. V. Milto,
И. В. Суходоло,
T. K. Klimentiyeva,
Н. М. Шевцова
Publication year - 2011
Publication title -
bulletin of siberian medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2018-3-48-53
Subject(s) - magnetite , hepatocyte , intracellular , spleen , magnetite nanoparticles , chemistry , enzyme , magnetic nanoparticles , nanoparticle , biophysics , pathology , biochemistry , microbiology and biotechnology , materials science , biology , medicine , immunology , nanotechnology , metallurgy , in vitro
After unitary and repeated intravenous application magnetite is shown their distribution in organism of a rat by method of magnetic resonance imaging. Accumulation of particles in a liver and a spleen of animals is shown. We studied intracellular activity main enzymes of hepatocyte and nephrocyte rats in various periods after intravenous application of nanoparticles magnetite by histochemical method. Intravenous application of magnetite is accompanied change of energetic and plastic metabolism of studied cells.

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