Open AccessFEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Author(s) -
Л. М. Огородова,
Vadim Govorun,
С. В. Федосенко,
М. А. Карнаушкина,
Irina V. Saltykova,
D. G. Alekseyev,
Ye. S. Kostrytikova,
Alexander V. Tyakht,
Anna Popenko
Publication year - 2014
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2014-5-55-61
Subject(s) - metagenomics , microbiology and biotechnology , citrobacter , enterobacter , biology , copd , pulmonary disease , proteobacteria , clostridium difficile , candida albicans , gut flora , bifidobacterium , lactobacillus , medicine , immunology , bacteria , antibiotics , genetics , 16s ribosomal rna , escherichia coli , gene
The article summarizes the results of studies on the composition of microbial communities in stool samples of patients with chronic obstructive pulmonary disease (COPD) compared with healthy volunteers using genome-metagenomic sequencing. It is shown that the microbial community of the intestine in COPD patients is characterized as diverse taxonomic composition of metagenomes that the healthy volunteers microbiota. In this case, the normal composition of intestinal microbiota in patients with COPD is exposed to the qualitative and quantitative modifications. In contrast to healthy volunteers, the intestinal microbiota in patients with COPD is characterized by the presence of representatives of the Proteobacteria , as Citrobacter , Enterobacter , Eggerthella , Proteus , Salmonella , Anaerococcus , Clostridium difficile , Pseudomonas , as well as higher insemination fungus genus Candida ( Candida dubliniensis and Candida albicans ).