Open AccessINVESTIGATED DYNAMICS OF ELIMINATION MAGNETITE NANOPARTICLES OF INHALED IN GUINEA PIGS
Author(s) -
Алексей Валерьевич Носарев,
Е. Е. Абраменко,
Л. В. Капилевич,
Е. Ю. Дьякова,
В. С. Селиванова
Publication year - 2014
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2014-1-62-66
Subject(s) - magnetite nanoparticles , inhalation , magnetite , guinea pig , nanoparticle , respiratory system , chemistry , biophysics , medicine , materials science , nanotechnology , magnetic nanoparticles , biology , anesthesia , metallurgy
The article presents the results of a study of the dynamics of histological changes in the guinea pigs respiratory tissues due the process of elimination after a long course of inhaled nanoparticles of magnetite. In the experimental animals lungs as a result of prolonged inhalation nanomagnetite developed an inflammatory reaction, the accumulation of Perls -positive cells. These changes were not even a month later, when the input of magnetite nanoparticles in laboratory animals.