Open AccessCHARACTERISTIC OF RESISTANCE OF ERYTHROCYTES IN CARDIOSURGICAL PATIENTS WITH VARIOUS DEGREE OF MANIFESTATION OF POSTPERFUSION HEMOLYSIS
Author(s) -
И. В. Мальцева
Publication year - 2013
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2013-1-69-74
Subject(s) - hemolysis , red cell , medicine , permeability (electromagnetism) , red blood cell , cell , membrane permeability , erythrocyte membrane , surgery , cardiology , chemistry , membrane , biochemistry
The resistance of red cells to the mechanic, osmotic, and acid factors, as well as the permeability of red-cell membrane to low-molecular hydrophilic substances in patients with ischemic heart disease (IHD) with moderate (24 patients) and pronounced (13 patients) hemolysis after surgery under conditions of cardia bypass has been studied. It is found that the development of pronounced hemolysis (in contrast to the moderate one) is associated with the high permeability of the red-cell membrane before surgery at the reduced acid and mechanic resistance of cells, which decreases after surgery and combines with normalization of acid resistance of red cells with the red-cell membrane permeability kept at the initially high level. The osmotic resistance of red cells in IHD patients is increased regardless of the level of hemolysis and the stage of the study, and its minimal level is observed only in patients with moderate hemolysis before surgery.