
The role of galectin-1 in the T-lymphocytes homeostasis
Author(s) -
V. D. Yakushina,
O. A. Vasiliyeva,
N. V. Ryazantsevа,
V. V. Novitsky,
O. Ye. Chechina,
Т. С. Прохоренко,
Ye. G. Starikova
Publication year - 2011
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2011-6-93-99
Subject(s) - homeostasis , microbiology and biotechnology , signal transduction , immune system , biology , cell , galectin , t cell , immunology , genetics
Fault in T-lymphocytes homeostasis leads to different diseases with poor or vise versa strong immune response. So it seems to be interesting to research molecules of T-cell cooperation to develop new more effective therapeutic methods. Important factor modulating T-cell activity is galectin-1 which takes part in multiply process of cell biology — regulation of cell maturation, migration, signal transduction, functional ability and apoptosis.