Open AccessExperimental study of 4-aminobenzoilgidrazid succinic acid antidiabetic activity
Author(s) -
V. P. Kotegov,
N. V. Kolotova,
I. P. Bulatov,
M. Yu. Bludova,
G. N. Pestov,
A. I. Andreyev
Publication year - 2011
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2011-5-66-69
Subject(s) - succinic acid , diabetes mellitus , chemistry , insulin , medicine , endocrinology , pharmacology , biochemistry
In experiments on intact rats and rats with steroid diabetes was studied the effects of prolonged introduction of 4-aminobenzoilgidrazid of succinic acid. It is shown that this substance potentiates the hypoglycemic effect of insulin, increases glucose tolerance and reduces the hyperglycemic effect of adrenaline.