Open AccessNew plant agents with cerebroprotective effect
Author(s) -
V. N. Burkova,
А. И. Венгеровский,
Н. И. Суслов,
A. V. Kaigorodtsev,
O. N. Nasanova,
A. I. Yatsenkov,
Ye. I. Grishina,
Ye. V. Melik-Gaikazyan,
L. L. Fisanova
Publication year - 2011
Publication title -
bûlletenʹ sibirskoj mediciny
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 3
eISSN - 1819-3684
pISSN - 1682-0363
DOI - 10.20538/1682-0363-2011-5-29-35
Subject(s) - urtica dioica , oxidative phosphorylation , antioxidant , substrate (aquarium) , mitochondrion , valerian , biology , biochemistry , chemistry , pharmacology , botany , ecology
The meadowsweet (Filipendula vulgaris) extract in a greater degree, than valerian extract improves in albino rat's brain the kinetic characteristics of mitochondrion respiratory activity, increases the association of substrate oxidation with ADP phosphorylation in experimental posthypoxic encephalopathy. The nettle (Urtica dioica) extract increases in albino rat's brain the rate of cycle Krebs substrate utilization and oxidative phosphorylation coupling in experimental inhibition of fatty acids p-oxidation caused with 4-pentenoic acid. The meadowsweet and nettle extracts posses the expressed antioxidant effect.